TNF -308G > a promoter polymorphism (rs1800629) and outcome from critical illness

BACKGROUND: The susceptibility to adverse outcome from critical illness (occurrence of sepsis, septic shock, organ dysfunction/failure, and mortality) varies dramatically due to different degrees of inflammatory response. An over expression of tumor necrosis factor alpha (TNF-α) can lead to the prog...

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Bibliographic Details
Main Authors: Diego D'Ávila Paskulin, Paulo RV Fallavena, Francis JO Paludo, Thiago J Borges, Juliane B Picanço, Fernando S Dias, Clarice Sampaio Alho
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300009&lng=en&tlng=en