N-terminal region is responsible for mHv1 channel activity in MDSCs

N-terminal region is responsible for mHv1 channel activity in MDSCs

Voltage-gated proton channels (Hv1) are important regulators of the immunosuppressive function of myeloid-derived suppressor cells (MDSCs) in mice and have been proposed as a potential therapeutic target to alleviate dysregulated immunosuppression in tumors. However, till date, there is a lack of ev...

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Bibliographic Details
Main Authors: Antonio Peña-Pichicoi, Miguel Fernández, Nieves Navarro-Quezada, Juan J. Alvear-Arias, Christian A. Carrillo, Emerson M. Carmona, Jose Garate, Angelica M. Lopez-Rodriguez, Alan Neely, Erick O. Hernández-Ochoa, Carlos González
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
voltage-gated proton channel
cloning
mHv1.1
mHv1.2
mHv1.3
myeloid-derived suppressor cells
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1265130/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1265130/full

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