Cloning and characterization of a novel functional organic anion transporting polypeptide 3A1 isoform highly expressed in the human brain and testis

Cloning and characterization of a novel functional organic anion transporting polypeptide 3A1 isoform highly expressed in the human brain and testis

Organic anion transporting polypeptide 3A1 (OATP3A1, encoded by the SLCO3A1 gene) is a prostaglandin, oligopeptide, and steroid/thyroid hormone transporter with wide tissue distribution, expressed, e.g., in the human brain and testis. Although the physiological importance of OATP3A1 has not yet been...

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Bibliographic Details
Main Authors: Éva Bakos, Orsolya Német, Nóra Kucsma, Natália Tőkési, Bruno Stieger, Elisabeth Rushing, Anna-Mária Tőkés, Péter Kele, Gábor E. Tusnády, Csilla Özvegy-Laczka
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
organic anion transporting polypeptide (OATP)
isoform
choroid plexus
testis
steroid transport
human brain
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.958023/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.958023/full

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