Analysis and verification of the circRNA regulatory network RNO_CIRCpedia_ 4214/RNO-miR-667-5p/Msr1 axis as a potential ceRNA promoting macrophage M2-like polarization in spinal cord injury

Analysis and verification of the circRNA regulatory network RNO_CIRCpedia_ 4214/RNO-miR-667-5p/Msr1 axis as a potential ceRNA promoting macrophage M2-like polarization in spinal cord injury

Abstract Background CircRNAs are involved in the pathogenesis of several central nervous system diseases. However, their functions and mechanisms in spinal cord injury (SCI) are still unclear. Therefore, the purpose of this study was to evaluate circRNA and mRNA expression profiles in the pathologic...

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Bibliographic Details
Main Authors: Jian Cao, Chongzhi Pan, Jian Zhang, Qi Chen, Tao Li, Dingwen He, Xigao Cheng
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Genomics
Subjects:
Spinal cord injury
Circular RNAs
Immune inflammation
Macrophages
Polarization
Online Access:https://doi.org/10.1186/s12864-023-09273-w

Internet

https://doi.org/10.1186/s12864-023-09273-w

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