A feasibility study of colorectal cancer diagnosis via circulating tumor DNA derived CNV detection.

Circulating tumor DNA (ctDNA) has shown great promise as a biomarker for early detection of cancer. However, due to the low abundance of ctDNA, especially at early stages, it is hard to detect at high accuracies while keeping sequencing costs low. Here we present a pilot stage study to detect large...

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Bibliographic Details
Main Authors: Bhuvan Molparia, Glenn Oliveira, Jennifer L Wagner, Emily G Spencer, Ali Torkamani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5965833?pdf=render