Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in Non-Small Cell Lung Cancer

Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in Non-Small Cell Lung Cancer

<p>Abstract</p> <p>Background</p> <p>Our previous studies have demonstrated that transduction of human dendritic cells (DC) with adenovirus encoding secondary lymphoid chemokine, CCL21, led to secretion of biologically active CCL21 without altering DC phenotype or viabi...

Full description

Bibliographic Details
Main Authors: Sharma Sherven, Batra Raj K, Zeng Gang, Kurimoto Pam S, Luo Jie, Peebles Katherine, Hazra Saswati, Takedatsu Hiroko, Baratelli Felicita, Dubinett Steven M, Lee Jay M
Format: Article
Language:English
Published: BMC 2008-07-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/38

Internet

http://www.translational-medicine.com/content/6/1/38

Similar Items