C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

The contribution of distinct subsets of macrophages to atherosclerosis is poorly understood. Here the authors describe a protective subset of vascular macrophages expressing the C-type lectin receptor CLEC4A2, which licenses monocytes to join the resident vascular macrophage pool and ensures vascula...

Full description

Bibliographic Details
Main Authors: Inhye Park, Michael E. Goddard, Jennifer E. Cole, Natacha Zanin, Leo-Pekka Lyytikäinen, Terho Lehtimäki, Evangelos Andreakos, Marc Feldmann, Irina Udalova, Ignat Drozdov, Claudia Monaco
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27862-9

Internet

https://doi.org/10.1038/s41467-021-27862-9

Similar Items