β-Hemolysin, not agrA mutation, inhibits the hemolysis of α-hemolysin in Staphylococcus aureus laboratory and clinical strains

ABSTRACTStaphylococcus aureus produces various hemolysins regulated by the Agr-QS system, except β-hemolysin encoded by the gene hlb. A classical laboratory S. aureus strain RN4220 displays only the β-hemolysin phenotype. It was suspected that the 8A mutation at the end of its agrA gene delayed the...

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Bibliographic Details
Main Authors: Lin Liu, Hemu Zhuang, Yanfei Wang, Yuexing Tu, Yunsong Yu, Yan Chen, Xueqing Wu
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00673-23