Bone Morphogenetic Protein 2 Promotes Bone Formation in Bone Defects in Which Bone Remodeling Is Suppressed by Long-Term and High-Dose Zoledronic Acid

The use of long-term and high-dose bisphosphate is associated with severely suppressed bone turnover and the delayed union of fractures. However, therapeutic methods to overcome the negative effects of bisphosphonate use are lacking. Bone morphogenetic proteins (BMPs) are powerful osteoinductive pro...

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Bibliographic Details
Main Authors: Young Jae Moon, Seongyup Jeong, Kwang-Bok Lee
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/1/86