Characterizing the polygenic overlap and shared loci between rheumatoid arthritis and cardiovascular diseases

Characterizing the polygenic overlap and shared loci between rheumatoid arthritis and cardiovascular diseases

Abstract Background Despite substantial research revealing that patients with rheumatoid arthritis (RA) have excessive morbidity and mortality of cardiovascular disease (CVD), the mechanism underlying this association has not been fully known. This study aims to systematically investigate the phenot...

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Bibliographic Details
Main Authors: Xiaohui Sun, Yu Qian, Weiqiu Cheng, Ding Ye, Bin Liu, Dan Zhou, Chengping Wen, Ole A. Andreassen, Yingying Mao
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Medicine
Subjects:
Rheumatoid arthritis
Cardiovascular diseases
Epidemiological association
Genetic correlation
Pleiotropic loci
Online Access:https://doi.org/10.1186/s12916-024-03376-1

Internet

https://doi.org/10.1186/s12916-024-03376-1

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