An Exploratory Study on the Contractile Effects of Hydroxy-α-Sanshool and Hydroxy-β-Sanshool, the Active Ingredients of Daikenchuto, on the Internal Anal Sphincter

Objectives: Daikenchuto (DKT) enhances the contraction of the internal anal sphincter (IAS) in patients with constipation and fecal incontinence; however, the mechanism of its action is unknown. We investigated the effects of the active ingredients of DKT (hydroxy-α-sanshool (HAS) and hydroxy-β-sans...

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Bibliographic Details
Main Authors: Kotaro Maeda, Toshinobu Sasaki
Format: Article
Language:English
Published: The Japan Society of Coloproctology 2023-07-01
Series:Journal of the Anus, Rectum and Colon
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jarc/7/3/7_2023-001/_pdf/-char/en