Evaluation of cell damage and modulation of cytokines TNF-α, IL-6 and IL-10 in macrophages exposed to PpIX-mediated photodynamic therapy

Evaluation of cell damage and modulation of cytokines TNF-α, IL-6 and IL-10 in macrophages exposed to PpIX-mediated photodynamic therapy

Abstract Little is known regarding whether photodynamic therapy (PDT)-induced cell death can substantially compromise macrophages (MΦ), which are important cells in PDT-induced immune responses. Here, parameters of PDT-mediated MΦ cytotoxicity and cytokine production in response to protoporphyrin IX...

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Bibliographic Details
Main Authors: R. D. R. Tiveron, D. A. Costa, M. D. I. Leite, C. B. S. Vaz, M. Sousa, S. M. C. F. Carlos, C. J. F. Oliveira, R. R. Machado, T. P. Paulino
Format: Article
Language:English
Published: Instituto Internacional de Ecologia 2019-09-01
Series:Brazilian Journal of Biology
Subjects:
photodynamic therapy
macrophage
DNA damage
cytokines
oxidative stress
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842020000300497&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842020000300497&tlng=en

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