Low levels of peripheral blood activated and senescent T cells characterize people with HIV-1-associated neurocognitive disorders

Low levels of peripheral blood activated and senescent T cells characterize people with HIV-1-associated neurocognitive disorders

BackgroundHIV infection induces a 75% increase in the risk of developing neurocognitive impairment (NCI), which has been linked to immune activation. We therefore looked for immune activation markers correlating with NCI.MethodSixty-five people aged 55-70 years living with controlled HIV-1 infection...

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Bibliographic Details
Main Authors: Lucy Kundura, Renaud Cezar, Manuela Pastore, Christelle Reynes, Jérémy Deverdun, Emmanuelle Le Bars, Albert Sotto, Jacques Reynes, Alain Makinson, Pierre Corbeau
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
cognition
T cell activation
T cell senescence
inflammation
neuroimaging
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267564/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267564/full

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