Ginsenoside CK, rather than Rb1, possesses potential chemopreventive activities in human gastric cancer via regulating PI3K/AKT/NF-κB signal pathway

Ginsenoside CK, rather than Rb1, possesses potential chemopreventive activities in human gastric cancer via regulating PI3K/AKT/NF-κB signal pathway

Ginsenoside Rb1, a main component of ginseng, is often transformed into ginsenoside CK by intestinal flora to exert various pharmacological activity. However, it remains unclear whether ginsenoside CK is responsible for the anti-gastric cancer effect of ginsenoside Rb1 in vivo. In this study, networ...

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Bibliographic Details
Main Authors: Yan Wan, Dong Liu, Jia Xia, Jin-Feng Xu, Li Zhang, Yu Yang, Jiao-Jiao Wu, Hui Ao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
ginsenoside Rb1
ginsenoside CK
gastric cancer
network pharmacology
apoptosis
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.977539/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.977539/full

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