At the center of cervical carcinogenesis: synergism between high-risk HPV and the hyperactivated YAP1

Human papillomavirus (HPV) is recognized as a necessary, but insufficient cause of cervical cancer. Recent in vitro and in vivo evidence from our laboratory demonstrate that hyperactivation of yes-associated protein 1 (YAP1) is sufficient to induce cervical carcinogenesis. We found that synergism be...

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Bibliographic Details
Main Authors: Cheng Wang, John S Davis
Format: Article
Language:English
Published: Taylor & Francis Group 2019-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2019.1612677