Genetic polymorphisms are associated with individual susceptibility to dexmedetomidine

Genetic polymorphisms are associated with individual susceptibility to dexmedetomidine

Introduction: Dexmedetomidine (DXM) is widely used as an adjuvant to anesthesia or a sedative medicine, and differences in individual sensitivity to the drug exist. This study aimed to investigate the effect of genetic polymorphisms on these differences.Methods: A total of 112 patients undergoing ha...

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Bibliographic Details
Main Authors: Yuanyuan Ding, Aiqing Liu, Yafeng Wang, Shuai Zhao, Shiqian Huang, Hongyu Zhu, Lulin Ma, Linlin Han, Shaofang Shu, Lidong Zheng, Xiangdong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Genetics
Subjects:
dexmedetomidine
pharmacogenomics
sedation
single nucleotide polymorphism
susceptibility
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1187415/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1187415/full

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