Synaptic and mitochondrial mechanisms behind alcohol-induced imbalance of excitatory/inhibitory synaptic activity and associated cognitive and behavioral abnormalities

Abstract Alcohol consumption during pregnancy can significantly impact the brain development of the fetus, leading to long-term cognitive and behavioral problems. However, the underlying mechanisms are not well understood. In this study, we investigated the acute and chronic effects of binge-like al...

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Bibliographic Details
Main Authors: Thiago Arzua, Yasheng Yan, Xiaojie Liu, Ranjan K. Dash, Qing-Song Liu, Xiaowen Bai
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-02748-8