Mitigation of BMP-induced inflammation in craniofacial bone regeneration and improvement of bone parameters by dietary hesperidin

Mitigation of BMP-induced inflammation in craniofacial bone regeneration and improvement of bone parameters by dietary hesperidin

Abstract Based on anti-inflammatory and osteogenic properties of hesperidin (HE), we hypothesized its systemic administration could be a cost-effective method of improving BMP-induced bone regeneration. Sprague–Dawley rats were allocated into 4 groups (n = 10/group): a 5-mm critical-sized mandible d...

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Bibliographic Details
Main Authors: Patricia A. Miguez, Vinícius de Paiva Gonçalves, Marta L. Musskopf, Angeliz Rivera-Concepcion, Skylar McGaughey, Christina Yu, Dong Joon Lee, Stephen A. Tuin, Aya Ali
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52566-7

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https://doi.org/10.1038/s41598-024-52566-7

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