FSHR-mTOR-HIF1 signaling alleviates mouse follicles from AMPK-induced atresia

Summary: The majority of activated ovarian follicles undergo atresia during reproductive life in mammals, and only a small number of follicles are ovulated. Though hormone treatment has been widely used to promote folliculogenesis, the molecular mechanism behind follicle selection and atresia remain...

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Bibliographic Details
Main Authors: Longping Liu, Ming Hao, Jianyun Zhang, Ziqi Chen, Jiaqi Zhou, Chao Wang, Hua Zhang, Jianbin Wang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723011701