<i>Dyrk1a</i> from Gene Function in Development and Physiology to Dosage Correction across Life Span in Down Syndrome

Down syndrome is the main cause of intellectual disabilities with a large set of comorbidities from developmental origins but also that appeared across life span. Investigation of the genetic overdosage found in Down syndrome, due to the trisomy of human chromosome 21, has pointed to one main driver...

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Bibliographic Details
Main Authors: Helin Atas-Ozcan, Véronique Brault, Arnaud Duchon, Yann Herault
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/11/1833