Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors

Although family B G protein-coupled receptors (GPCRs) contain only 15 members, they play key roles in transmembrane signal transduction of hormones. Family B GPCRs are drug targets for developing therapeutics for diseases ranging from metabolic to neurological disorders. Despite their importance, th...

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Bibliographic Details
Main Authors: Kelly J Culhane, Yuting eLiu, Yingying eCai, Elsa C. Y. Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00264/full