Serotonin modulates excitatory synapse maturation in the developing prefrontal cortex

Serotonin modulates excitatory synapse maturation in the developing prefrontal cortex

Abstract Serotonin (5-HT) imbalances in the developing prefrontal cortex (PFC) are linked to long-term behavioral deficits. However, the synaptic mechanisms underlying 5-HT-mediated PFC development are unknown. We found that chemogenetic suppression and enhancement of 5-HT release in the PFC during...

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Bibliographic Details
Main Authors: Roberto Ogelman, Luis E. Gomez Wulschner, Victoria M. Hoelscher, In-Wook Hwang, Victoria N. Chang, Won Chan Oh
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45734-w

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https://doi.org/10.1038/s41467-024-45734-w

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