Core <italic toggle="yes">N</italic>-Glycan Structures Are Critical for the Pathogenicity of <named-content content-type="genus-species">Cryptococcus neoformans</named-content> by Modulating Host Cell Death

Core <italic toggle="yes">N</italic>-Glycan Structures Are Critical for the Pathogenicity of <named-content content-type="genus-species">Cryptococcus neoformans</named-content> by Modulating Host Cell Death

ABSTRACT Cryptococcus neoformans is a human-pathogenic fungal pathogen that causes life-threatening meningoencephalitis in immunocompromised individuals. To investigate the roles of N-glycan core structure in cryptococcal pathogenicity, we constructed mutant strains of C. neoformans with defects in...

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Bibliographic Details
Main Authors: Eun Jung Thak, Su-Bin Lee, Shengjie Xu-Vanpala, Dong-Jik Lee, Seung-Yeon Chung, Yong-Sun Bahn, Doo-Byoung Oh, Mari L. Shinohara, Hyun Ah Kang
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
Cryptococcus neoformans
N-linked protein glycosylation
ALG
fungal pathogenesis
Online Access:https://journals.asm.org/doi/10.1128/mBio.00711-20

Internet

https://journals.asm.org/doi/10.1128/mBio.00711-20

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