Primitive genotypic characteristics in umbilical cord neutrophils identified by single-cell transcriptome profiling and functional prediction

The function and heterogeneity of neutrophils in neonatal umbilical cord blood (UCB) have not been characterized. In this study, we analyzed the neutrophils in UCB and healthy adults using single-cell RNA sequencing analysis for the first time. We found that neutrophils divided into six subpopulatio...

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Bibliographic Details
Main Authors: Yi Chen, Jiamin Huang, Zaiwen Guo, Zhechen Zhu, Yiming Shao, Linbin Li, Yunxi Yang, Yanzhen Yu, Lu Liu, Bingwei Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.970909/full