Virtual nuclear envelope breakdown and its regulators in fission yeast meiosis

Ran, a small GTPase, is required for the spindle formation and nuclear envelope (NE) formation. After NE breakdown (NEBD) during mitosis in metazoan cells, the Ran-GTP gradient across the NE is lost and Ran-GTP becomes concentrated around chromatin, thus affecting the stability of microtubules and p...

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Bibliographic Details
Main Authors: Haruhiko eAsakawa, Hui-Ju eYang, Yasushi eHiraoka, Tokuko eHaraguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00005/full