Alteration of homeostasis in pre-osteoclasts induced by Aggregatibacter actinomycetemcomitans CDT

The dysbiotic microbiota associated with aggressive periodontitis includes Aggregatibacter actinomycetemcomitans, the only oral species known to produce a cytolethal distending toxin (AaCDT). Given that CDT alters the cytokine profile in monocytic cells, we aimed to test the hypothesis that CDT play...

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Bibliographic Details
Main Authors: Dione eKawamoto, Ellen Sayuri Ando-Sugimoto, Bruno eBueno-Silva, Joseph M. DiRienzo, Marcia Pinto Alves Mayer
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00033/full