<i>Carissa macrocarpa</i> Leaves Polar Fraction Ameliorates Doxorubicin-Induced Neurotoxicity in Rats via Downregulating the Oxidative Stress and Inflammatory Markers

<i>Carissa macrocarpa</i> Leaves Polar Fraction Ameliorates Doxorubicin-Induced Neurotoxicity in Rats via Downregulating the Oxidative Stress and Inflammatory Markers

Chemotherapeutic-related toxicity exacerbates the increasing death rate among cancer patients, necessitating greater efforts to find a speedy solution. An in vivo assessment of the protective effect of the <i>C. macrocarpa</i> leaves polar fraction of hydromethanolic extract against doxo...

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Bibliographic Details
Main Authors: Mohamed A. A. Orabi, Heba M. A. Khalil, Mohamed E. Abouelela, Dalia Zaafar, Yasmine H. Ahmed, Reham A. Naggar, Hamad S. Alyami, El-Shaymaa Abdel-Sattar, Katsuyoshi Matsunami, Dalia I. Hamdan
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceuticals
Subjects:
<i>Carissa macrocarpa</i>
cytotoxicity
UPLC-ESI-MS/MS
doxorubicin
neurotoxicity
molecular docking
Online Access:https://www.mdpi.com/1424-8247/14/12/1305

Internet

https://www.mdpi.com/1424-8247/14/12/1305

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