Microglia, seen from the CX3CR1 angle

Microglial cells in brain and spinal cord are characterized by high expression of the chemokine receptor CX3CR1. Expression of the sole CX3CR1 ligand, the membrane-tethered and sheddable chemokine CX3CL1/ fractalkine, is restricted in the brain parenchyma to selected neurons. Here we summarize our c...

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Bibliographic Details
Main Authors: Yochai eWolf, Simon eYona, Ki-Wook eKim, Steffen eJung
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00026/full