B cell MHC haplotype affects follicular inclusion, germinal center participation and plasma cell differentiation in a mouse model of lupus

B cell MHC haplotype affects follicular inclusion, germinal center participation and plasma cell differentiation in a mouse model of lupus

IntroductionMHC class II molecules are essential for appropriate immune responses against pathogens but are also implicated in pathological responses in autoimmune diseases and transplant rejection. Previous studies have shed light on the systemic contributions of MHC haplotypes to the development a...

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Bibliographic Details
Main Authors: Camilla Wibrand, Thomas R. Wittenborn, Lasse Frank Voss, Gudrun Winther, Lisbeth Jensen, Alexey Ferapontov, Sofie V. Fonager, Cecilia Fahlquist-Hagert, Søren E. Degn
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
B cells
MHC
autoimmunity
autoantibodies
germinal centers
complement
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1258046/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1258046/full

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