Intravenous iron supplementation in heart failure patients induces temporary endothelial dysfunction with release of endothelial microvesicles

BackgroundIntravenous iron supplementation is an established therapy for patients with heart failure (HF) and concomitant iron deficiency reducing the risk of HF hospitalization. However, concerns persist regarding potential adverse vascular effects, since iron may induce oxidative stress, inflammat...

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Bibliographic Details
Main Authors: Sebastian F. Mause, Martin Berger, Hwee Ying Lim, Felix Vogt, Vincent Brandenburg, Robert Stöhr
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1092704/full