Delineating functional and molecular impact of ex vivo sample handling in precision medicine

Delineating functional and molecular impact of ex vivo sample handling in precision medicine

Abstract Consistent handling of samples is crucial for achieving reproducible molecular and functional testing results in translational research. Here, we used 229 acute myeloid leukemia (AML) patient samples to assess the impact of sample handling on high-throughput functional drug testing, mass sp...

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Bibliographic Details
Main Authors: Nona Struyf, Albin Österroos, Mattias Vesterlund, Cornelia Arnroth, Tojo James, Stephanie Sunandar, Georgios Mermelekas, Anna Bohlin, Kerstin Hamberg Levedahl, Sofia Bengtzén, Rozbeh Jafari, Lukas M. Orre, Janne Lehtiö, Sören Lehmann, Päivi Östling, Olli Kallioniemi, Brinton Seashore-Ludlow, Tom Erkers
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00528-7

Internet

https://doi.org/10.1038/s41698-024-00528-7

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