Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length

Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length

Animal cells within a tissue typically display a striking regularity in their size. To date, the molecular mechanisms that control this uniformity are still unknown. We have previously shown that size uniformity in animal cells is promoted, in part, by size-dependent regulation of G1 length. To iden...

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Bibliographic Details
Main Authors: Shixuan Liu, Miriam Bracha Ginzberg, Nish Patel, Marc Hild, Bosco Leung, Zhengda Li, Yen-Chi Chen, Nancy Chang, Yuan Wang, Ceryl Tan, Shulamit Diena, William Trimble, Larry Wasserman, Jeremy L Jenkins, Marc W Kirschner, Ran Kafri
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
cell size
cell cycle
cell growth control
p38 MAPK pathway
high-content screening
Online Access:https://elifesciences.org/articles/26947

Internet

https://elifesciences.org/articles/26947

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