Gene cascade analysis in human granulosa tumor cells (KGN) following exposure to high levels of free fatty acids and insulin

Abstract Maternal metabolic disorders such as obesity and diabetes are detrimental factors that compromise fertility and the success rates of medically assisted procreation procedures. During metabolic stress, adipose tissue is more likely to release free fatty acids (FFA) in the serum resulting in...

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Bibliographic Details
Main Authors: Patricia G. Tremblay, Chloé Fortin, Marc-André Sirard
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-021-00934-6