Visualization of SARS-CoV-2 particles in naso/oropharyngeal swabs by thin section electron microscopy

Abstract Background SARS-CoV-2 replicates efficiently in the upper airways of humans and produces high loads of virus RNA and, at least in the initial phase after infection, many infectious virus particles. Studying virus ultrastructure, such as particle integrity or presence of spike proteins, and...

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Bibliographic Details
Main Authors: Michael Laue, Tobias Hoffmann, Janine Michel, Andreas Nitsche
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-023-01981-9