Xanthene derivatives increase glucose utilization through activation of LKB1-dependent AMP-activated protein kinase.

Xanthene derivatives increase glucose utilization through activation of LKB1-dependent AMP-activated protein kinase.

5' AMP-activated protein kinase (AMPK) is a highly conserved serine-threonine kinase that regulates energy expenditure by activating catabolic metabolism and suppressing anabolic pathways to increase cellular energy levels. Therefore AMPK activators are considered to be drug targets for treatme...

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Bibliographic Details
Main Authors:	Yonghoon Kwon, Parkyong Song, Jong Hyuk Yoon, Jaewang Ghim, Dayea Kim, Byungjun Kang, Taehoon G Lee, Jin-Ah Kim, Joong-Kwon Choi, In Kwon Youn, Hyeon-Kyu Lee, Sung Ho Ryu
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4177559?pdf=render

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