Limb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women.

Advancements in animal models and cell culture techniques have been invaluable in the elucidation of the molecular mechanisms that regulate muscle atrophy. However, few studies have examined muscle atrophy in humans using modern experimental techniques. The purpose of this study was to examine chang...

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Bibliographic Details
Main Authors: Arkan Abadi, Elisa I Glover, Robert J Isfort, Sandeep Raha, Adeel Safdar, Nobuo Yasuda, Jan J Kaczor, Simon Melov, Alan Hubbard, Xiaoyan Qu, Stuart M Phillips, Mark Tarnopolsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2716517?pdf=render