Tumor-associated macrophages and response to 5-fluorouracil adjuvant therapy in stage III colorectal cancer

Tumor-associated macrophages and response to 5-fluorouracil adjuvant therapy in stage III colorectal cancer

Tumor-associated macrophages (TAMs) play a role in tumor development and progression. We hypothesized that abundance of TAMs might modify efficacy of 5-fluorouracil chemotherapy in colorectal cancer. We measured the density of CD68+ TAMs at the invasive front of primary tumor of colorectal carcinoma...

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Bibliographic Details
Main Authors: Alberto Malesci, Paolo Bianchi, Giuseppe Celesti, Gianluca Basso, Federica Marchesi, Fabio Grizzi, Giuseppe Di Caro, Tommaso Cavalleri, Lorenza Rimassa, Richard Palmqvist, Alessandro Lugli, Viktor. H. Koelzer, Massimo Roncalli, Alberto Mantovani, Shuji Ogino, Luigi Laghi
Format: Article
Language:English
Published: Taylor & Francis Group 2017-12-01
Series:OncoImmunology
Subjects:
adjuvant therapy
colorectal cancer
innate immunity
outcome
tumor associate macrophages
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1342918

Internet

http://dx.doi.org/10.1080/2162402X.2017.1342918

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