Selenoprotein K Increases Efficiency of DHHC6 Catalyzed Protein Palmitoylation by Stabilizing the Acyl-DHHC6 Intermediate

Selenoprotein K Increases Efficiency of DHHC6 Catalyzed Protein Palmitoylation by Stabilizing the Acyl-DHHC6 Intermediate

Selenoprotein K (SELENOK) is a selenocysteine (Sec)-containing protein localized in the endoplasmic reticulum (ER) membrane where it interacts with the DHHC6 (where single letter symbols represent Asp-His-His-Cys amino acids) enzyme to promote protein acyl transferase (PAT) reactions. PAT reactions...

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Bibliographic Details
Main Authors: Gregory J. Fredericks, FuKun W. Hoffmann, Robert J. Hondal, Sharon Rozovsky, Johann Urschitz, Peter R. Hoffmann
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Antioxidants
Subjects:
palmitic acid
palmitoyl-CoA
palmitoylation
inositol 1,4,5-triphosphate receptor
ANK repeat and PH domain-containing protein 2 (ASAP2)
cluster of differentiation (CD36)
selenium
thioester
Online Access:https://www.mdpi.com/2076-3921/7/1/4

Internet

https://www.mdpi.com/2076-3921/7/1/4

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