A neuron model with unbalanced synaptic weights explains the asymmetric effects of anaesthesia on the auditory cortex.

Substantial progress in the field of neuroscience has been made from anaesthetized preparations. Ketamine is one of the most used drugs in electrophysiology studies, but how ketamine affects neuronal responses is poorly understood. Here, we used in vivo electrophysiology and computational modelling...

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Bibliographic Details
Main Authors: Luciana López-Jury, Francisco García-Rosales, Eugenia González-Palomares, Johannes Wetekam, Michael Pasek, Julio C Hechavarria
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002013