Epithelial to Mesenchymal Transition in tumor cells as consequence of phenotypic instability

During the last years many articles have reported epithelial-to-mesenchymal transitions (EMT) induced by a myriad of gene products either when added to the cell medium or when transfected. Molecularly the EMT is characterized by the up-regulation of transcriptional factors (EMT-TFs) repressing the...

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Bibliographic Details
Main Author: Antonio eGarcia de Herreros
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00071/full