The structural basis of the talin–KANK1 interaction that coordinates the actin and microtubule cytoskeletons at focal adhesions
Adhesion between cells and the extracellular matrix is mediated by heterodimeric (αβ) integrin receptors that are intracellularly linked to the contractile actomyosin machinery. One of the proteins that control this link is talin, which organizes cytosolic signalling proteins into discrete complexes...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2023-06-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.230058 |