Minocycline attenuates cirrhotic cardiomyopathy and portal hypertension in a rat model: Possible involvement of nitric oxide pathway

Minocycline attenuates cirrhotic cardiomyopathy and portal hypertension in a rat model: Possible involvement of nitric oxide pathway

Objective(s): An increase in nitric oxide (NO) production has been reported in cirrhotic cardiomyopathy and, portal hypertension. Since minocycline has been shown to inhibit NO overproduction, we aimed to examine its role in a rat model of CCl4-induced cirrhotic cardiovascular complications. Materia...

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Bibliographic Details
Main Authors: Seyyedeh Elaheh Mousavi, Seyed Mahdi Rezayat, Maliheh Nobakht, Seyed Soheil Saeedi Saravi, Iraj Yazdani, Amir Rashidian, Ahmad Reza Dehpour
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Cirrhotic cardiomyopathy Minocycline
Nitric Oxide
Portal Hypertension
Rat
Online Access:http://ijbms.mums.ac.ir/article_7823_cb2ee387918bc6f932aaec337085108f.pdf

Internet

http://ijbms.mums.ac.ir/article_7823_cb2ee387918bc6f932aaec337085108f.pdf

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