Resistance of M. leprae to quinolones: a question of relativity?

UNLABELLED:Multidrug resistant leprosy, defined as resistance to rifampin, dapsone and fluoroquinolones (FQ), has been described in Mycobacterium leprae. However, the in vivo impact of fluoroquinolone resistance, mainly mediated by mutations in DNA gyrase (GyrA2GyrB2), has not been precisely assesse...

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Bibliographic Details
Main Authors: Nicolas Veziris, Aurélie Chauffour, Sylvie Escolano, Sarah Henquet, Masanori Matsuoka, Vincent Jarlier, Alexandra Aubry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3828155?pdf=render