A new spontaneously transformed syngeneic model of high-grade serous ovarian cancer with a tumor-initiating cell population.

A new spontaneously transformed syngeneic model of high-grade serous ovarian cancer with a tumor-initiating cell population.

Improving screening and treatment options for patients with epithelial ovarian cancer has been a major challenge in cancer research. Development of novel diagnostic and therapeutic approaches, particularly for the most common subtype, high-grade serous ovarian cancer (HGSC), has been hampered by con...

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Bibliographic Details
Main Authors: Curtis W. McCloskey, Reuben L. Goldberg, Lauren E. Carter, Lisa F. Gamwell, Ensaf M. Al-Hujaily, Olga eCollins, Elizabeth A. Macdonald, Kenneth eGarson, Manijeh eDaneshmand, Euridice eCarmona, Barbara C. Vanderhyden
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Oncology
Subjects:
stem cell
Cancer stem cell
ovarian cancer
tumor initiating cells
ovarian surface epithelium
high grade serous cancer
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00053/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00053/full

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