Protein synthesis dependence of growth cone collapse induced by different Nogo-A-domains.

The protein Nogo-A regulates axon growth in the developing and mature nervous system, and this is carried out by two distinct domains in the protein, Nogo-A-Δ20 and Nogo-66. The differences in the signalling pathways engaged in axon growth cones by these domains are not well characterized, and have...

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Bibliographic Details
Main Authors: Richard Manns, Andre Schmandke, Antonio Schmandke, Prem Jareonsettasin, Geoffrey Cook, Martin E Schwab, Christine Holt, Roger Keynes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3906062?pdf=render