Growth and division mechanisms by which genetic resisters emerge from the rifampicin-surviving population of differentially antibiotic-susceptible mycobacterial subpopulations

Growth and division mechanisms by which genetic resisters emerge from the rifampicin-surviving population of differentially antibiotic-susceptible mycobacterial subpopulations

Background: We recently reported the de novo emergence of unusually high numbers of antibiotic resisters from the in vitro cultures of Mycobacterium tuberculosis and Mycobacterium smegmatis surviving in the presence of minimum bactericidal concentration (MBC) of antituberculosis antibiotics. The res...

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Bibliographic Details
Main Authors: Kishor Jakkala, Avraneel Paul, Rashmi Ravindran Nair, Sharmada Swaminath, Atul Pradhan, Parthasarathi Ajitkumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:International Journal of Mycobacteriology
Subjects:
antibiotic resistance
antibiotic-surviving population
cell number spurt
minor and major subpopulations
multinucleated
multiseptated
mycobacterium smegmatis
rifampicin
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2022;volume=11;issue=3;spage=273;epage=286;aulast=Jakkala

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http://www.ijmyco.org/article.asp?issn=2212-5531;year=2022;volume=11;issue=3;spage=273;epage=286;aulast=Jakkala

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