Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals

Background: Impaired lung function is predictive of mortality and is a key component of chronic obstructive pulmonary disease. Lung function has a strong genetic component but is also affected by environmental factors such as increased exposure to air pollution, but the effect of their interactions...

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Bibliographic Details
Main Authors: Carl A. Melbourne, A. Mesut Erzurumluoglu, Nick Shrine, Jing Chen, Martin D. Tobin, Anna L. Hansell, Louise V. Wain
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Environment International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412021006668