PPAR-γ agonist pioglitazone improves semen quality and testicular histomorphometrics with partial reversal of hyperglycaemia in alloxan-induced diabetic rats

Objective: Chronic hyperglycaemia is associated with subfertility and infertility in male diabetic subjects, possible as a result of perturbed testicular antioxidant defence system. Recent evidence however shows that some testicular cells produce insulin and this raises the possibility of a role for...

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Bibliographic Details
Main Authors: O.B. Akinola, O.O. Dosumu, S.A. Sanusi, T.F. Ajayi, T.H. Olajide
Format: Article
Language:English
Published: SpringerOpen 2015-12-01
Series:Middle East Fertility Society Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110569014200550