The Role of the Inhibitory Ligand HVEM and Its Receptors CD160 and BTLA in the Regulation of Anti-retroviral T Cell Responses

The Role of the Inhibitory Ligand HVEM and Its Receptors CD160 and BTLA in the Regulation of Anti-retroviral T Cell Responses

Specific CD8+ T cells are crucial for the control of viruses. However, during many chronic viral infections these cells become dysfunctional. Immune checkpoint receptors, like PD-1 expressed on CD8+ T cells, contribute to this functional suppression during chronic infection. However, during the acut...

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Bibliographic Details
Main Authors: Paul David, Jaana Westmeier, Malgorzata Drabczyk-Pluta, Tanja Werner, Julia Ickler, Sandra Francois, Wibke Bayer, Kathrin Sutter, Maria Luisa Del Rio, Jose-Ignacio Rodriguez-Barbosa, Ulf Dittmer, Gennadiy Zelinskyy
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Virology
Subjects:
immunoregulation
retrovirus
CD160
BTLA
HVEM
PD-L1
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.836291/full

Internet

https://www.frontiersin.org/articles/10.3389/fviro.2022.836291/full

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