Beneficial Effects of Isoflavones in the Kidney of Obese Rats Are Mediated by PPAR-Gamma Expression

Beneficial Effects of Isoflavones in the Kidney of Obese Rats Are Mediated by PPAR-Gamma Expression

Several studies have demonstrated an important association between altered lipid metabolism and the development of kidney injury because of a high-fat diet. Fructose is also closely associated with renal injury. We opted for a combination of fructose and saturated fats in a diet (DH) that is a model...

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Bibliographic Details
Main Authors: Edson de Andrade Pessoa, Márcia Bastos Convento, Bianca Castino, Ala Moana Leme, Andréia Silva de Oliveira, Alef Aragão, Sheila Marques Fernandes, Adriana Carbonel, Cassiane Dezoti, Maria de Fátima Vattimo, Nestor Schor, Fernanda Teixeira Borges
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Nutrients
Subjects:
high-fat/high-fructose diet
nephropathy
isoflavones
PPAR-γ
angiotensin II
oxidative stress
Online Access:https://www.mdpi.com/2072-6643/12/6/1624

Internet

https://www.mdpi.com/2072-6643/12/6/1624

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